Hi, https://mega.nz/#!csdUUCSB!4upNDtTOnnqg-R4Jh5piMWO_2KGmLPq7N56W9eFJpX8 

Runlog.txt and Saves\<savefile> are within "Siege of Centauri.zip" 

If it is of any help, but this is just me guessing: I believe the issue is related to the Windows 10 1809 Audio issues which are still not fully solved by Microsoft yet.

After disabling ALL my audio devices in the device manager (and/or Control>Sounds) I was able to complete the map and had some more attempts at the next one - so if you need a Runlog.txt of the time that specific crash with the savegame appeared, I might need to re-do it again. The savegame is still valid for my situation though (but reproducible => audio active either instant-crash or once I place the next unit, no audio at all (muting is not enough) - it was fine.) 

(Drivers are all up to date, I can also provide a DXDiag if required.)

Cheers

this time, mission 7, instantly on loading the savegame. regardless if my audio devices are activated or not. 

I can restart and play the entire mission from scratch and it will reliably crash once I either lose my HQ or I win the mission - the game simply crashes and autocloses, the progress has not been saved, the mission is not yet marked as completed.

Save\<savegame>,RunLog.txt and a current DXDiag.txt are included in the zip file located here:

https://mega.nz/#!Ek031YwK!0M4makaCrbEOM8BmAEs0LUXFQS5cTOwISwS0fg-cx1c