Can you upload the minidumps you are getting with these crashes? Dropbox can be used to upload them.
Try going through this list of troubleshooting and taking the steps not already taken and if the game is still crashing:
-Does it work if you start in dev mode? (Click the arrow beside Play in the launcher and check “Use Dev Exe”)
-Disable any Nahimic sound stuff.
-Verify you have the latest graphic drivers.
-In the NVIDIA control panel try different scaling settings.
-Try different resolutions.
-Try reducing any in-game graphic settings.
-Right click > options > compatibility > disable fullscreen optimisation
-Verify the game cache
-Go to Windows Defender->Virus and Threat Protection->Virus and Threat Protection Settings->Manage Controlled Folder Access and try removing the Sins install folder.
-Go to the game install folder. Right click on sins of a solar empire rebellion.exe, select properties, compatability. check the box for disable fullscreen optimization. then click change high dpi settings. check both boxes in the next menu and have it use the dpi setting when windows starts.