I haven't played the game in a while, but I do remember playing it on my box a few months ago. Since then, I haven't installed anything fancy on the box (it's basically used for games and development).
Today, I wanted to play. The game crashed when I wanted to start a skirmish. Nothing makes much sense, the GPU drivers are still the same (AMD 15.7.1), but then Visual Studio did update several time, but it should still be compatible.