First I should mention that at turn 186 in an Immense game, I started running into very frequent freezes (not CTDs). I then loaded the OPTIN patch 2. I then was able to continue, and the performance seemed much better (I have 8gb memory). So far so good!
Now on to the meat...of course I was very interested in the culture bug and the Hot Fix. In the game mentioned above, namely
https://www.dropbox.com/s/9e4gz76vktlzhom/Culture
%20Check.GC3Sav?dl=0
if anyone wants to check it out. There was a "blob of doom" that had appeared near one of my colonies. After the patch...it was gone. Great.
I did look over the map, however, and did see a couple of situations that seemed odd...although, to be sure, I am not at all certain, on thinking about it, that these aren't exactly as expected. However, as I say, they do look a bit curious.