I have noticed that I can't save a game, I have autosave turned off in case of the disappearing turn button (which still disappears, btw). So when the turn button goes away and I save a game, there's nothing to load when I restart GCII, so GCII crashes to desktop. Permissions seem to be ok on the GCII directory, but the game doesn't save. At least I can't find it in any of the drengin or stardock folders.
My system:
Asus A7V333 w/Athlon XP 1700+
1 Gig ram
AIW 9600 pro w/5.3 drivers