Well, one time on StarCraft II my main base was destroyed, but I had a backup base. With "dormant" factories, soldiers, and workers. It was well hidden and well defended. With this secret base, I destroyed the Empire... er, I mean Zerg.
EDIT: If you didn't get that Star Wars joke, my faith in humanity just lessened a little bit. If you got it and didn't think it was funny, it's ok, I didn't either.
Also, on most strategy games, I keep a couple of Transports filled with workers and soldiers at the least, and epic secret bases at the most.
My point is, don't just assume someone is down because you crippled them. You ever hear about that blind kid with ecoloction, or the armless guy with the robotic hand? Or that monkey that does math?
Those guys are crippled, and they went and got all badass and stuff. Except the monkey, he was always badass.