Its all about the bombers Advent have the best strikecraft, and you can send those things to do your dirty work from the other side of the grav well. Upgrade-wise, I think it depends on what you're using the starbase for - meteors are awesome for taking out a fleet, fighters/bombers are best if you want to be able to hit anywhere in the grav well (but are redundant if you're building somewhere you can also build hangers) and so on.

front line = armor and meteor but you can do wathewer you want if a tec guy come with ogrov you starbase is just a waste of money

use fleets advents have the best one so use it

For attacking Ogrevs, you want meteors and mass disorientation. I know meteors have range to hit Ogrevs, and I'm pretty sure MA does, too. Regular weapons, though, won't work.

MA does not it is short by 2000, meteors does (its right on the money 12000 for both meteor and Ogrevs)  but when the TEC researches missile range Ogrevs outreach meteors

Yeah, once I started to think about it (although the repulse idea with the Guardians is AWESOME) there are alot of ways I could have handled it better. However I was pretty stupid when it came to upgrading that starbase.

I just like asking questions apparently, so in your opinion is there ever a time to upgrade a starbase with Culture, and if so, how many and when?

And I think I've decided to stick with Weapons/Armor/Meteor/Disorient for upgrades with my front line starbases. Is there any reason to deviate from this and go with something different, say Fighters/Bombers?

Best time to use the culture upgrade: 1, on a starbase protecting inner portions of your empire (like a wormhole for example), 2. If your opponent is technologically inferior (ie doesnt have much culture of his own), then you can use culture to grab his border planets without firing a shot, or prevent him from taking a contested planet.

As for bombers/fighters, most of the time its difficult for an opponent to tell what upgrades you have on your SB. If you upgrade its health to full, an opponent may assume its weapons or abilities have been upgraded and doesnt want to send a fleet up against it, so theyll opt for bombers or assault cruisers, in which case upgrading fighter capacity may help protect your SB, or if your opponent has more strikecraft than you, upgrading the hangars may help even the score.

Depends on what your up against, but I will say, If you're going to be using meteors, you dont really need that second weapons upgrade. And you can actually do without the weapons upgrades completely if youve got disorient and a bunch of synergized beam turrets. I would highly recommend using homming mines (build a hangar bay or two to get them) in any front line situation. Theyll soften your opponents fleet considerably for your defenses, or cause heavy damage to fleets trying to bypass them.