Regarding a strategy, I usually put points into his acid spit, fury, and movement/attack speed skills. I also put points into the very bottom skill, which improves his regular attack. I typically put one point into the stun/life drain so that I can stun.
I try to use items that increase his movement speed, attack speed, and attack damage. I generally start with boots of speed as my first purchase, then buy a set of armor and a helmet, then purchase the mage slayer from the artifact shop. With a fast attack speed, high damage, and acid spit, I usually fare pretty well against enemy demigods 1 v 1, and my fast movement speed allows me to quickly get to enemies who are under attack by my friends so I can join in.
Also, I think there is a better strategy guide in the strategies guides section of this forum.
