Saturn2888, there is nice tool for multiscreen support - ultramon
http://www.realtimesoft.com/ultramon/
you can lock cursor in primary screen. so, in case that you run game in window, your cursor wont move out of primary screen.
also it has more nice features - like adding taskbar for secondary screen - it will display all windows running on secondary screen etc etc.
but i would like to know if someone knows if there is any way how to release cursor from primary screen(in case that you are running game in fullscreen mode) and manage secondary screen(without minimalizing fullscreen application in primary window).