Thanks guys for the input. Unfortunately, I am getting these runtime crashes on a fresh install. I have 3 machines in my house. One with Vista 32 bit, which is playable, but I have to save every 5 minutes for the inpending crashes. Another machine with the Win 7 Beta running on it, and while all of my games work on this, Sins crashes instantly when loaded. lol.. The only machine that does not get these runtime crashes, is the XP machine, which I have demoted to my storage closet bascially.
One thing I will check is the dotnet version on the Win 7 machine. It is possible that's an issue there. The Vista machine has dotnet ver 3, so... *shrugs*
But thanks guys. I appreciate the help. 